Ryanodine Receptor Calcium Release Channel

A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.

Also Known As:

Ryanodine Receptor; Ca Release Channel-Ryanodine Receptor; Receptor, Ryanodine; RyR2; RyR3; Ca Release Channel Ryanodine Receptor; Calcium Ryanodine Receptor Complex; Complex, Calcium-Ryanodine Receptor; Receptor 1, Ryanodine; Receptor 2, Ryanodine; Receptor 3, Ryanodine; Receptor Complex, Calcium-Ryanodine; Receptors, Ryanodine; Calcium-Ryanodine Receptor Complex; RyR1; Ryanodine Receptor 1; Ryanodine Receptor 2; Ryanodine Receptor 3; Ryanodine Receptors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Carrier Proteins: 13306
    - Membrane Transport Proteins: 606
      - Ion Channels: 6936
        Calcium Channels: 3531
        Ryanodine Receptor Calcium Release Channel: 2144
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Ion Channels: 6936
        Calcium Channels: 3531
        Ryanodine Receptor Calcium Release Channel: 2144
    - Membrane Transport Proteins: 606
      - Ion Channels: 6936
        Calcium Channels: 3531
        Ryanodine Receptor Calcium Release Channel: 2144
  - Contractile Proteins: 703
    - Muscle Proteins: 1603
      - Ryanodine Receptor Calcium Release Channel: 2144

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Disease

Drug/Important Bio-Agent (IBA)